21
Mai
2005

Microwaves from GSM Mobile Phones Affect 53BP1 and y-H2AX Foci in Human Lymphocytes from Hypersensitive and Healthy Persons

//ehp.niehs.nih.gov/docs/2005/7561/abstract.html

Microwaves from GSM Mobile Phones Affect 53BP1 and y-H2AX Foci in Human Lymphocytes from Hypersensitive and Healthy Persons ... those effects are presently ignored by International Commission for Non-Ionizing Radiation Protection (ICNIRP) safety stands.

HOT Off The Press

DNA damage from Mobile Phones
"... is ignored by the International Commission for Non-Ionizing Radiation Protection (ICNIRP) safety stands ..."

A quote from the abstract below, "... The 53BP1 and y-H2AX proteins, which have been shown to co-localize in distinct foci with DNA double strand breaks (DSBs), were analyzed by immunofluorescence confocal laser microscopy ..."


Environmental Health Perspectives
EHP - in - Press
(Research Article, Archives ... week of 4/23 to 4/29)
(Online Apr 26, 2005)
//ehp.niehs.nih.gov/docs/admin/newest.html#4_23

Abstract ... This abstract is on page 6 ... see PDF links at ... //ehp.niehs.nih.gov/members/2005/7561/7561.pdf

The data on biological effects of non-thermal microwaves (MW's) from mobile phones are diverse and those effects are presently ignored by the International Commission for Non-Ionizing Radiation Protection (ICNIRP) safety standards. Here, we investigated effects of MWs of Global System for Mobile Communication (GSM) at different carrier frequencies on human lymphocytes from healthy persons and from persons reporting hypersensitivity to electromagnetic fields (EMFs). The changes in chromatin conformation, which are indicative of stress response and gennotoxic effects, were measured by the method of anomalous viscosity time dependencies (AVTD). The 53BP1 and y-H2AX proteins, which have been shown to co-localize in distinct foci with DNA double strand breaks (DSBs), were analyzed by immunofluorescence confocal laser microscopy. We show that MWs from GSM mobile phone affect chromatin conformation and 53BP1/y-H2AX foci similar to heat shock.

For the first time, we report here that MWs from mobile phone affect 53BP1/y-H2AX foci are dependent on carrier frequency. In average, the same response was observed in lymphocytes from hypersensitive and healthy subjects.


Website address is ...
//ehp.niehs.nih.gov/docs/2005/7561/abstract.html

Research Article

Microwaves from GSM Mobile Phones Affect 53BP1 and -H2AX Foci in Human Lymphocytes from Hypersensitive and Healthy Persons

Eva Markovà, Lena Hillert, Lars Malmgren, Bertil R. R. Persson, and Igor Y. Belyaev

Abstract

//ehp.niehs.nih.gov/docs/2005/7561/abstract.pdf
Abstract in PDF

This EHP-in-Press article has been peer-reviewed, revised, and accepted for publication. The EHP-in-Press articles are completely citable using the assigned DOI code for the article. This document will be replaced with the copyedited and formatted version as soon as it is available. Through the DOI number used in the citation, you will be able to access this document at each stage of the publication process. Environ Health Perspect doi:10.1289/ehp.7561 available via //dx.doi.org/ [Online 28 April 2005]

The full version of this article is available for free in //ehp.niehs.nih.gov/members/2005/7561/7561.pdf
PDF format.



Informant: Sepp Hasslberger


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