Clinical Data on EMR Exposures
Subject: Dr Carlo letter is in the BMJ rapid responses
http://www.bmj.com/cgi/eletters/334/7606/1249#168843
The position being taken by Goldacre in his commentary that provocation studies are definitive in assessing electromagnetic radiation (EMR) health risks is simply incorrect. Current information on the pathological mechanism involved in EMR-related disease makes clear that laboratory constructs that do not have close approximation to real-world exposures are of little value in assessing these risks.
For the past five years, through our Safe Wireless Initiative project, we have operated the only post-market surveillance database in the world systematically collecting symptom information from thousands of patients suffering from the effects of various types of EMR exposure. In addition, we coordinate a network of clinicians who regularly share information about their experiences treating patients with these conditions, another important and unique resource. Thus, we do not rely solely on self-reported information but have corroboration from treating doctors. It is noteworthy that our post-market surveillance registry will open in the UK soon. This is an important public health step because in the UK, there are no reliable data on the incidence and prevalence of EMR- related conditions. With no real data, speculations are all the more misinformed.
We regularly share summary information from our registry database in various fora around the world, including a February 2007 presentation at the House of Commons, for the benefit of clinicians and patients alike. Goldacre seems to be relying only on one type of data in his assessment, while ignoring clinical realities.
Overall, our post-market surveillance data show patterns that suggest an emerging medical and public health problem.
There are symptom and pathology similarities among patients suffering from electro-hypersensitivity, multiple chemical sensitivities, alcohol- related disease as well as neuro-behavioral and learning disorders. We are now referring to the symptom constellations as Membrane Sensitivity Syndrome (MSS) and the increase in reports of symptoms consistent with MSS associated by patients with various EMR exposures has dramatically increased over the past 24 months.
It is noteworthy that concurrently in the past 24 months, the penetration of mobile phones has tripled globally, from one billion to three billion. WiFi has reached the highest penetration in history. Satellite radio is not far behind. All of these technologies rely on information-carrying radio waves, the trigger for non-thermal adverse biological responses and the cascade toward MSS.
In a majority of MSS cases, when EMR is removed from the patient's environment, their acute symptoms subside. This is an important observation and indeed represents one of the Koch-Henle postulates for causation: If when the exposure is removed, the effect is diminished, there is evidence for cause and effect.
Pathology and experimental findings support a mechanistic underpinning: an environmentally induced genetic change that renders daughter cells to carry membrane sensitivity characteristics with most symptoms directly or indirectly the result of consequent disrupt of intercellular communication.
Therapeutic intervention regimens designed around known EMR mechanisms of harm have positively shown varying degrees of clinical symptom amelioration, another support for the causal hypothesis, but more importantly, a ray of hope for those afflicted and debilitated by these conditions.
It is a fact that every serious public health problem man has faced has first been identified through clinical observations, the historically confirmed first line of evidence for preventing epidemic spread of disease. It is a disservice to clinicians and patients when uninformed speculation serves to lessen the acuity with which important early signs that can alleviate suffering are seen and heeded.
Dr. George L. Carlo
Science and Public Policy Institute
1101 Pennsylvania Ave. NW -- 7th Floor Washington, D.C. 20004
http://www.sppionline.org
http://www.safewireless.org
202-756-7744
Competing interests: None declared
From Mast Sanity/Mast Network
--------
Lack of Science, terrible science, no science
http://www.buergerwelle.de/pdf/lack_of_science_terrible_science_no_science.htm
[ Non-Thermal Effects: http://www.i-sis.org.uk/FOI3.php
this article may not be readable in "Lack of Science, terrible science, no science"]
Informant: Martin Weatherall
http://omega.twoday.net/search?q=Carlo
http://omega.twoday.net/search?q=Goldacre
http://omega.twoday.net/search?q=EMR+exposures
http://omega.twoday.net/search?q=electromagnetic+radiation
http://omega.twoday.net/search?q=hypersensitive
http://omega.twoday.net/search?q=Membrane+Sensitivity+Syndrome
http://freepage.twoday.net/search?q=Goldacre
http://www.bmj.com/cgi/eletters/334/7606/1249#168843
The position being taken by Goldacre in his commentary that provocation studies are definitive in assessing electromagnetic radiation (EMR) health risks is simply incorrect. Current information on the pathological mechanism involved in EMR-related disease makes clear that laboratory constructs that do not have close approximation to real-world exposures are of little value in assessing these risks.
For the past five years, through our Safe Wireless Initiative project, we have operated the only post-market surveillance database in the world systematically collecting symptom information from thousands of patients suffering from the effects of various types of EMR exposure. In addition, we coordinate a network of clinicians who regularly share information about their experiences treating patients with these conditions, another important and unique resource. Thus, we do not rely solely on self-reported information but have corroboration from treating doctors. It is noteworthy that our post-market surveillance registry will open in the UK soon. This is an important public health step because in the UK, there are no reliable data on the incidence and prevalence of EMR- related conditions. With no real data, speculations are all the more misinformed.
We regularly share summary information from our registry database in various fora around the world, including a February 2007 presentation at the House of Commons, for the benefit of clinicians and patients alike. Goldacre seems to be relying only on one type of data in his assessment, while ignoring clinical realities.
Overall, our post-market surveillance data show patterns that suggest an emerging medical and public health problem.
There are symptom and pathology similarities among patients suffering from electro-hypersensitivity, multiple chemical sensitivities, alcohol- related disease as well as neuro-behavioral and learning disorders. We are now referring to the symptom constellations as Membrane Sensitivity Syndrome (MSS) and the increase in reports of symptoms consistent with MSS associated by patients with various EMR exposures has dramatically increased over the past 24 months.
It is noteworthy that concurrently in the past 24 months, the penetration of mobile phones has tripled globally, from one billion to three billion. WiFi has reached the highest penetration in history. Satellite radio is not far behind. All of these technologies rely on information-carrying radio waves, the trigger for non-thermal adverse biological responses and the cascade toward MSS.
In a majority of MSS cases, when EMR is removed from the patient's environment, their acute symptoms subside. This is an important observation and indeed represents one of the Koch-Henle postulates for causation: If when the exposure is removed, the effect is diminished, there is evidence for cause and effect.
Pathology and experimental findings support a mechanistic underpinning: an environmentally induced genetic change that renders daughter cells to carry membrane sensitivity characteristics with most symptoms directly or indirectly the result of consequent disrupt of intercellular communication.
Therapeutic intervention regimens designed around known EMR mechanisms of harm have positively shown varying degrees of clinical symptom amelioration, another support for the causal hypothesis, but more importantly, a ray of hope for those afflicted and debilitated by these conditions.
It is a fact that every serious public health problem man has faced has first been identified through clinical observations, the historically confirmed first line of evidence for preventing epidemic spread of disease. It is a disservice to clinicians and patients when uninformed speculation serves to lessen the acuity with which important early signs that can alleviate suffering are seen and heeded.
Dr. George L. Carlo
Science and Public Policy Institute
1101 Pennsylvania Ave. NW -- 7th Floor Washington, D.C. 20004
http://www.sppionline.org
http://www.safewireless.org
202-756-7744
Competing interests: None declared
From Mast Sanity/Mast Network
--------
Lack of Science, terrible science, no science
http://www.buergerwelle.de/pdf/lack_of_science_terrible_science_no_science.htm
[ Non-Thermal Effects: http://www.i-sis.org.uk/FOI3.php
this article may not be readable in "Lack of Science, terrible science, no science"]
Informant: Martin Weatherall
http://omega.twoday.net/search?q=Carlo
http://omega.twoday.net/search?q=Goldacre
http://omega.twoday.net/search?q=EMR+exposures
http://omega.twoday.net/search?q=electromagnetic+radiation
http://omega.twoday.net/search?q=hypersensitive
http://omega.twoday.net/search?q=Membrane+Sensitivity+Syndrome
http://freepage.twoday.net/search?q=Goldacre
Starmail - 17. Jun, 19:08
