3
Sep
2005

2.45GHz radiofrequency fields alter gene expression in cultured human cells

Lee S, Johnson D, Dunbar K, Dong H, Ge X, Kim YC, Wing C, Jayathilaka N, Emmanuel N, Zhou CQ, Gerber HL, Tseng CC, Wang SM.

Department of Medicine, University of Chicago, Chicago, IL 60637, USA.

The biological effect of radiofrequency (RF) fields remains controversial. We address this issue by examining whether RF fields can cause changes in gene expression. We used the pulsed RF fields at a frequency of 2.45GHz that is commonly used in telecommunication to expose cultured human HL-60 cells. We used the serial analysis of gene expression (SAGE) method to measure the RF effect on gene expression at the genome level. We observed that 221 genes altered their expression after a 2-h exposure. The number of affected genes increased to 759 after a 6-h exposure. Functional classification of the affected genes reveals that apoptosis-related genes were among the upregulated ones and the cell cycle genes among the downregulated ones. We observed no significant increase in the expression of heat shock genes. These results indicate that the RF fields at 2.45GHz can alter gene expression in cultured human cells through non-thermal mechanism.

PMID: 16107253 [PubMed - in process]

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16107253&dopt=Citation


From FGF-Infoline 02.09.2005
logo

Omega-News

User Status

Du bist nicht angemeldet.

Suche

 

Archiv

September 2005
Mo
Di
Mi
Do
Fr
Sa
So
 
 
 
 
 
 

Aktuelle Beitr├Ąge

Störungen des Nervensystems...
Störungen des Nervensystems bei Arbeitern von...
Starmail - 13. Apr, 04:55
Klimaerwärmung und...
Elektromagnetische Wellen erzeugen Schwingungen und...
Starmail - 30. Mrz, 18:33
Cell phone tower radiation...
"A study conducted by three departments of Panjab University...
Starmail - 25. Feb, 09:02
The Effect of Cell Phone...
http://www.buergerwelle.de /pdf/cluster.jpg German...
Starmail - 25. Feb, 09:01
Many cancer patients...
HARIAN Metro front-paged a report that more than eight...
Starmail - 25. Feb, 08:56

Status

Online seit 3799 Tagen
Zuletzt aktualisiert: 9. Jun, 05:15

Credits

vi knallgrau GmbH

powered by Antville powered by Helma

twoday.net AGB