Effect of microwave irradiation on neurocyte mitochondrial ultrastructure and mtTFA mRNA expression in rats cerebral cortex
[Article in Chinese]
* Xie Y,
* Jiang HH,
* Gong QF,
* Zhang GB,
* Yu JH,
* Yu ZP.
Department of Military Labor Hygiene, Third Military Medical University, Chongqing 400038, China.
OBJECTIVE: To explore molecular controlling mechanism of mitochondrial injury induced by different density of microwave irradiation.
METHODS: Rats were exposed to microwave irradiation for 1 hour at average power density of 3 mW/cm(2) or 30 mW/cm(2). After microwave irradiation, the changes of pathological ultrastructure of rat cerebral cortex and hippocampus were observed by electron microscope, and mitochondrial transcription factor A (mtTFA) mRNA expression level were determined by RT-PCR.
RESULTS: After 3 mW/cm(2) microwave irradiation for 0, 3, 24 h, mitochondrial ultrastructure and mtTFA mRNA expression level didn't significantly change in rat cerebral cortex and hippocampus. After 30 mW/cm(2) microwave irradiation for 0, 3, 24 h, mitochondrial ultrastructure obviously changed, mtTFA mRNA expression in rat hippocampus significantly increased by 67.00%, 80.00%, 30.00% respectively, and in rat cerebral cortex by 133.00%, 86.00%, 233.00% respectively. There were significant differences between the corresponding groups of hippocampus and cerebral cortex (P < 0.01). CONCLUSION: No obvious change in mitochondria was found after 3 mW/cm(2) microwave irradiation, but it was found after 30 mW/cm(2) microwave irradiation. Mitochondria injury in cerebral cortex was more severe than that in hippocampus. mtTFA mRNA may have certain regulation in mitochondrial energy metabolism.
PMID: 15130438 [PubMed - indexed for MEDLINE]
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15130438&dopt=Abstract
Informant: Paul Doyon
--------
Mitochondria
Regarding this study : http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15130438&dopt=Abstract I discovered something interesting at this address : http://www.sante.univ-nantes.fr/med/biolcell/mitochondrie/index.htm in bottom of the page, there are two tables giving the diseases in English. Well, EMF are acting everywhere and activating so much kind of diseases that it's easy to the operators to say: this is impossible... prove it... By the way, WHO is organizing a workshop, look: http://www.who.int/peh-emf/meetings/elf_emf_workshop_2007/en/index.html
Philippe Hug
CP 17
CH-1454 L'Auberson
Switzerland
http://www.alerte.ch
A message to the bona fide EMF research community:
The premise of the study that WHO is proposing for the workshop cited below is wrong......
Their Invitation states that the "goals" of the workshop are limited to: "low cost health economics" recommendations. .... "To discuss the cost and feasibility of different options."
Doesn't that put the cart before the horse? It sounds like George Bush's criterion in the Global Warming scenario...... Only those options which do not disturb the "economic development" parameters will be pursued. That is code word language for:
PROFITS ARE MORE IMPORTANT THAN PEOPLE.
It is the exact opposite of the premise that should guide mankind's attack on such global 'health and environmental' threatening matters -- which includes the EMF scenario.
Until mankind succeeds in reversing that premise to something like, "PEOPLE ARE MORE IMPORTANT THAN PROFITS," ... very little progress will be made.
If mankind cannot rely on WHO to turn such "global" health and environmental threats to criteria that put people ahead of profits -- then, I ask, who will???
Cheerio......
Roy Beavers (EMFguru)
http://www.emfguru.org/
http://omega.twoday.net/search?q=World+Health+Organization
* Xie Y,
* Jiang HH,
* Gong QF,
* Zhang GB,
* Yu JH,
* Yu ZP.
Department of Military Labor Hygiene, Third Military Medical University, Chongqing 400038, China.
OBJECTIVE: To explore molecular controlling mechanism of mitochondrial injury induced by different density of microwave irradiation.
METHODS: Rats were exposed to microwave irradiation for 1 hour at average power density of 3 mW/cm(2) or 30 mW/cm(2). After microwave irradiation, the changes of pathological ultrastructure of rat cerebral cortex and hippocampus were observed by electron microscope, and mitochondrial transcription factor A (mtTFA) mRNA expression level were determined by RT-PCR.
RESULTS: After 3 mW/cm(2) microwave irradiation for 0, 3, 24 h, mitochondrial ultrastructure and mtTFA mRNA expression level didn't significantly change in rat cerebral cortex and hippocampus. After 30 mW/cm(2) microwave irradiation for 0, 3, 24 h, mitochondrial ultrastructure obviously changed, mtTFA mRNA expression in rat hippocampus significantly increased by 67.00%, 80.00%, 30.00% respectively, and in rat cerebral cortex by 133.00%, 86.00%, 233.00% respectively. There were significant differences between the corresponding groups of hippocampus and cerebral cortex (P < 0.01). CONCLUSION: No obvious change in mitochondria was found after 3 mW/cm(2) microwave irradiation, but it was found after 30 mW/cm(2) microwave irradiation. Mitochondria injury in cerebral cortex was more severe than that in hippocampus. mtTFA mRNA may have certain regulation in mitochondrial energy metabolism.
PMID: 15130438 [PubMed - indexed for MEDLINE]
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15130438&dopt=Abstract
Informant: Paul Doyon
--------
Mitochondria
Regarding this study : http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15130438&dopt=Abstract I discovered something interesting at this address : http://www.sante.univ-nantes.fr/med/biolcell/mitochondrie/index.htm in bottom of the page, there are two tables giving the diseases in English. Well, EMF are acting everywhere and activating so much kind of diseases that it's easy to the operators to say: this is impossible... prove it... By the way, WHO is organizing a workshop, look: http://www.who.int/peh-emf/meetings/elf_emf_workshop_2007/en/index.html
Philippe Hug
CP 17
CH-1454 L'Auberson
Switzerland
http://www.alerte.ch
A message to the bona fide EMF research community:
The premise of the study that WHO is proposing for the workshop cited below is wrong......
Their Invitation states that the "goals" of the workshop are limited to: "low cost health economics" recommendations. .... "To discuss the cost and feasibility of different options."
Doesn't that put the cart before the horse? It sounds like George Bush's criterion in the Global Warming scenario...... Only those options which do not disturb the "economic development" parameters will be pursued. That is code word language for:
PROFITS ARE MORE IMPORTANT THAN PEOPLE.
It is the exact opposite of the premise that should guide mankind's attack on such global 'health and environmental' threatening matters -- which includes the EMF scenario.
Until mankind succeeds in reversing that premise to something like, "PEOPLE ARE MORE IMPORTANT THAN PROFITS," ... very little progress will be made.
If mankind cannot rely on WHO to turn such "global" health and environmental threats to criteria that put people ahead of profits -- then, I ask, who will???
Cheerio......
Roy Beavers (EMFguru)
http://www.emfguru.org/
http://omega.twoday.net/search?q=World+Health+Organization
Starmail - 19. Mai, 09:29
